Immunological Sciences

CD82 Rabbit Monoclonal Antibody

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Catalog Number:MABN87171
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD82
Reactivity:Human
Applications:WB 1:1000-1:5000
Molecular Weight:Calculated MW:30 kDa; Observed MW:30-60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human CD82

Target Background

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms:R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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