Immunological Sciences

CD89 Rabbit Monoclonal Antibody

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Catalog Number:MABN21201
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD89
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:300,ICC/IF 1:100-1:300,FC 1:100-1:300,IP 1:50-1:100
Molecular Weight:CalcuLated MW:;Observed MW:32kD
Purification:Protein A
Form:Liquid
Synonyms:FCAR;CD89;ImmunoglobuLin alpha Fc receptor ;IgA Fc receptor;CD antigen CD89;

Applications

WB 1:1000-1:5000,IHC 1:100-1:300,ICC/IF 1:100-1:300,FC 1:100-1:300,IP 1:50-1:100

Immunogen

A synthetic peptide of human CD89

Target Background

Cell localization:[Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; [Isoform B]: Secreted.; [Isoform B-delta-S2]: Secreted..This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Synonyms:FCAR;CD89;ImmunoglobuLin alpha Fc receptor ;IgA Fc receptor;CD antigen CD89;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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