Immunological Sciences

Cdc23/APC8 Rabbit Monoclonal Antibody

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Catalog Number:MABN83868
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human CDC23
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200
Molecular Weight:Calculated MW: 69 kDa ; Observed MW: 64 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8;;CDC23

Applications

WB 1:1000-1:2000,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human CDC23

Target Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms:CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8;;CDC23

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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