Immunological Sciences

CDC45L Rabbit Monoclonal Antibody

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Catalog Number:MABN86507
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CDC45L
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:66 kDa; Observed MW:66 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDC45L; MGORS7; CDC45L2; PORC-PI-1

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human CDC45L

Target Background

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Synonyms:CDC45L; MGORS7; CDC45L2; PORC-PI-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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