Immunological Sciences

Cdc6 (14X12) Rabbit Monoclonal Antibody

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Catalog Number:MABN08528
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Cdc6
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200
Molecular Weight:63kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CDC6; CDC18L; CDC6-related protein; Cdc18-related protein; HsCDC6; HsCDC18; p62(cdc6);

Applications

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human Cdc6

Target Background

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication. Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.

Synonyms:CDC6; CDC18L; CDC6-related protein; Cdc18-related protein; HsCDC6; HsCDC18; p62(cdc6);

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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