Immunological Sciences

CDK9 Mouse Monoclonal Antibody

No images available

Catalog Number:MABN80986
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CDK9 expressed in E. Coli.
Reactivity:Human,Mouse,Rat,Rabbit,Monkey
Applications:IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:43kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TAK; C-2k; CTK1; CDC2L4; PITALRE

Applications

IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human CDK9 expressed in E. Coli.

Target Background

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

Synonyms:TAK; C-2k; CTK1; CDC2L4; PITALRE

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

No documents available.