CDT2 Rabbit Monoclonal Antibody

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Catalog Number:MABN01814
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human CDT2
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 79 kDa; Observed MW: 79 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDW1; DCAF2; Dtl; L2DTL; RAMP

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

Recombinant protein of human CDT2

Target Background

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).

Synonyms:CDW1; DCAF2; Dtl; L2DTL; RAMP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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