Immunological Sciences

Cdx2 Rabbit Polyclonal Antibody

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Catalog Number:ABN08594
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CDX2. AA range:249-298
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:10000
Molecular Weight:45kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Applications

WB 1:500-1:2000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human CDX2. AA range:249-298

Target Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

Synonyms:CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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