Immunological Sciences

CEA(CD66e) (7M6) Rabbit Monoclonal Antibody

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Catalog Number:MABN08610
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Carcino Embryonic Antigen CEA
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:2000-1:20000,ICC/IF 1:200-1:500,FC 1:200-1:500
Molecular Weight:77kDa
Purification:Affinity purification
Form:Liquid
Synonyms:adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100;

Applications

WB 1:500-1:2000,IHC 1:2000-1:20000,ICC/IF 1:200-1:500,FC 1:200-1:500

Immunogen

Recombinant protein of human Carcino Embryonic Antigen CEA

Target Background

Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).

Synonyms:adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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