Immunological Sciences

CENPC (9Q1) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN08637
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human CENPC
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,FC 1:200-1:500,IP 1:50-1:200
Molecular Weight:107kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CENP-C; CENPC1; hcp-4; ICEN7; MIF2;

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,FC 1:200-1:500,IP 1:50-1:200

Immunogen

Recombinant protein of human CENPC

Target Background

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Synonyms:CENP-C; CENPC1; hcp-4; ICEN7; MIF2;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.