Immunological Sciences

cGAS Rabbit Monoclonal Antibody

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Catalog Number:MABN87482
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse cGAS
Reactivity:Mouse
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:58 kDa; Observed MW:58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Mb21d1; E330016A19Rik

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of mouse cGAS

Target Background

The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Synonyms:Mb21d1; E330016A19Rik

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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