CHMP2B Rabbit Monoclonal Antibody

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Catalog Number:MABN84605
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human CHMP2B
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 24 kDa ; Observed MW: 28 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ALS17; CHMP2b; DMT1; hVps2-2; VPS2B;;CHMP2B

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human CHMP2B

Target Background

Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

Synonyms:ALS17; CHMP2b; DMT1; hVps2-2; VPS2B;;CHMP2B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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