Immunological Sciences

CHRNE Mouse Monoclonal Antibody

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Catalog Number:MABN82074
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CHRNE (AA: extra 21-239) expressed in E. Coli.
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:54.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human CHRNE (AA: extra 21-239) expressed in E. Coli.

Target Background

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Synonyms:ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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