Immunological Sciences

CIDE-3 Rabbit Polyclonal Antibody

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Catalog Number:ABN08812
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CIDEC. AA range:189-238
Reactivity:Human,Rat,Mouse
Applications:IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000
Purification:Affinity purification
Form:Liquid
Synonyms:CIDEC; FSP27; Cell death activator CIDE-3; Cell death-inducing DFFA-like effector protein C; Fat-specific protein FSP27 homolog

Applications

IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human CIDEC. AA range:189-238

Target Background

cell death inducing DFFA like effector c(CIDEC) Homo sapiens This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],function:Isoforms 1 and 2 induce apoptosis.,similarity:Contains 1 CIDE-N domain.,subcellular location:Cytoplasmic in a punctate manner.,tissue specificity:Expressed mainly in small intestine, heart, colon and stomach and, at lower levels, in brain, kidney and liver.,

Synonyms:CIDEC; FSP27; Cell death activator CIDE-3; Cell death-inducing DFFA-like effector protein C; Fat-specific protein FSP27 homolog

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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