Immunological Sciences

Claudin-2 Mouse Monoclonal Antibody(8H11)

No images available

Catalog Number:MABN08905
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG
Clone:Monoclonal
Immunogen:Synthesized peptide derived from human Claudin-2
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:500,ICC/IF 1:100-1:500
Molecular Weight:25kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Claudin-2 (SP82)

Applications

WB 1:500-1:2000,IHC 1:100-1:500,ICC/IF 1:100-1:500

Immunogen

Synthesized peptide derived from human Claudin-2

Target Background

This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010],function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,

Synonyms:Claudin-2 (SP82)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

No documents available.