Immunological Sciences

Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody

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Catalog Number:ABN00828
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
Reactivity:Human,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000
Molecular Weight:Calculated MW: 33 kDa; Observed MW: 20,35 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179

Target Background

Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Synonyms:CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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