Clusterin alpha Chain Rabbit Monoclonal Antibody

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Catalog Number:MABN01836
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse Clusterin beta chain
Reactivity:Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 52 kDa; Observed MW: 42 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

Recombinant protein of mouse Clusterin beta chain

Target Background

Functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself.

Synonyms:Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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