Immunological Sciences

COL7A1 Rabbit Polyclonal Antibody

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Catalog Number:ABN09198
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890
Reactivity:Human,Mouse
Applications:IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000
Purification:Affinity purification
Form:Liquid
Synonyms:COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen

Applications

IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890

Target Background

collagen type VII alpha 1 chain(COL7A1) Homo sapiens This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008],disease:Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica (DEB) [MIM:131750, 226600].

Synonyms:COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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