Immunological Sciences

Connexin 43/GJA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87760
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Connexin 43/GJA1
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:43 kDa; Observed MW:43 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HSS; CMDR; CX43; EKVP; GJAL; ODDD; AVSD3; EKVP3; HLHS1; PPKCA

Applications

WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human Connexin 43/GJA1

Target Background

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

Synonyms:HSS; CMDR; CX43; EKVP; GJAL; ODDD; AVSD3; EKVP3; HLHS1; PPKCA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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