Immunological Sciences

Connexin 46 Rabbit Polyclonal Antibody

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Catalog Number:ABN09234
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GJA3. AA range:151-200
Reactivity:Human,Mouse,Rat
Applications:IHC 1:100-1:500,ICC/IF 1:100-1:500,ELISA 1:5000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:GJA3; Gap junction alpha-3 protein; Connexin-46; Cx46

Applications

IHC 1:100-1:500,ICC/IF 1:100-1:500,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human GJA3. AA range:151-200

Target Background

The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010],disease:Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. CZP3 is a form of autosomal dominant congenital cataract.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and non-junctional ("hemi-") channels.,

Synonyms:GJA3; Gap junction alpha-3 protein; Connexin-46; Cx46

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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