COPS4 Rabbit Monoclonal Antibody

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Catalog Number:MABN84736
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human COPS4
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 46 kDa ; Observed MW: 50 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CH4; COPS4; CSN4; DCH4; SGN4;;COPS4

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human COPS4

Target Background

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2.

Synonyms:CH4; COPS4; CSN4; DCH4; SGN4;;COPS4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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