COX2 Rabbit Monoclonal Antibody

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Catalog Number:MABN87843
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human COX2
Reactivity:Human, Mouse, Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:100
Molecular Weight:Calculated MW:69 kDa; Observed MW:74 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

Applications

WB 1:500-1:2000,IHC 1:100-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:100

Immunogen

A synthetic peptide of human COX2

Target Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Synonyms:COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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