Immunological Sciences

CREB3 Rabbit Monoclonal Antibody

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Catalog Number:MABN86881
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CREB3
Reactivity:Human
Applications:WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:Calculated MW:41 kDa; Observed MW:41 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:LZIP; LUMAN; sLZIP

Applications

WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human CREB3

Target Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]

Synonyms:LZIP; LUMAN; sLZIP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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