Immunological Sciences

Cripto1 (12R19) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN09398
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Cripto1
Reactivity:Human
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:21kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CRGF; Cripto 1; cripto; Cripto1 growth factor; TDGF1;

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of human Cripto1

Target Background

Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Synonyms:CRGF; Cripto 1; cripto; Cripto1 growth factor; TDGF1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.