Immunological Sciences

Cripto1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86584
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Cripto1
Reactivity:Human
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:21 kDa; Observed MW:18, 20 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:V1S4; TCRGV4

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of human Cripto1

Target Background

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).2 PublicationsGO - Molecular functioni

Synonyms:V1S4; TCRGV4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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