CrkL Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN86720
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CrkL
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:50-1:100
Molecular Weight:Calculated MW:34 kDa; Observed MW:39 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Crk-like protein

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:50-1:100

Immunogen

A synthetic peptide of human CrkL

Target Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]

Synonyms:Crk-like protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.