Immunological Sciences

CRMP1 (17O10) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN09411
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CRMP1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:1000-1:5000,ICC/IF 1:200-1:500,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:62,74kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CRMP 1; Crmp1; DPYSL1; DRP1; ULIP-3; Ulip3;

Applications

WB 1:500-1:2000,IHC 1:1000-1:5000,ICC/IF 1:200-1:500,FC 1:20-1:50,IP 1:20-1:50

Immunogen

A synthetic peptide of human CRMP1

Target Background

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:25358863). Plays a role in axon guidance (PubMed:25358863). During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863). Involved in invasive growth and cell migration (PubMed:11562390). May participate in cytokinesis (PubMed:19799413).

Synonyms:CRMP 1; Crmp1; DPYSL1; DRP1; ULIP-3; Ulip3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

No documents available.