Crotonyl-Histone H2B (Lys12) Rabbit Monoclonal Antibody

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Catalog Number:MABN87546
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic crotonylpeptide corresponding to residues surrounding Lys12 of human Histone H2B
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:14 kDa; Observed MW:14 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Crotonyl-Histone H2B (Lys12) Rabbit Monoclonal Antibody

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200

Immunogen

A synthetic crotonylpeptide corresponding to residues surrounding Lys12 of human Histone H2B

Target Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:Crotonyl-Histone H2B (Lys12) Rabbit Monoclonal Antibody

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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