Immunological Sciences

CRX (13O19) Rabbit Monoclonal Antibody

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Catalog Number:MABN09431
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CORD2
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,IF-P 1:200-1:500
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Cone rod homeobox; CORD 2; CRD; CRX; LCA7; OTX3;

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,IF-P 1:200-1:500

Immunogen

A synthetic peptide of human CORD2

Target Background

Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.

Synonyms:Cone rod homeobox; CORD 2; CRD; CRX; LCA7; OTX3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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