CRYAA (15B3) Rabbit Monoclonal Antibody

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Catalog Number:MABN09434
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human alpha A Crystallin
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:500
Molecular Weight:20kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Acry 1; CRYA1; CRYAA; HspB4;

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:500

Immunogen

A synthetic peptide of human alpha A Crystallin

Target Background

May contribute to the transparency and refractive index of the lens. Contributes to the transparency and refractive index of the lens (PubMed:18302245). In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions (PubMed:22120592, PubMed:31792453, PubMed:18199971, PubMed:19595763). Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed:28935373).

Synonyms:Acry 1; CRYA1; CRYAA; HspB4;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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