Immunological Sciences

CTPS Rabbit Polyclonal Antibody

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Catalog Number:ABN09513
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000
Molecular Weight:67kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1

Applications

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109

Target Background

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],catalytic activity:ATP + UTP + NH(3) = ADP + phosphate + CTP.,enzyme regulation:Activated by GTP and inhibited by CTP.,function:Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.,pathway:Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.,similarity:Belongs to the CTP synthase family.,similarity:Contains 1 glutamine amidotransferase type-1 domain.,

Synonyms:CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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