CXCR4 Rabbit Monoclonal Antibody

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Catalog Number:MABN83746
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human CXCR4
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200
Molecular Weight:Calculated MW: 40 kDa ; Observed MW: 43 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;;CXCR4

Applications

WB 1:500-1:1000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human CXCR4

Target Background

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

Synonyms:CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;;CXCR4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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