Cytokeratin 14 (11A9) Rabbit Monoclonal Antibody

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Catalog Number:MABN09723
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Cytokeratin 14
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:200-1:500
Molecular Weight:52kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CK-14; CK14; cytokeratin 14; Cytokeratin-14; EBS3; EBS4; K14; K1C14; keratin 14; Keratin, type I cytoskeletal 14; Keratin-14; KRT14; NFJ;

Applications

WB 1:2000-1:20000,IHC 1:200-1:500

Immunogen

A synthetic peptide of human Cytokeratin 14

Target Background

K14 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Synonyms:CK-14; CK14; cytokeratin 14; Cytokeratin-14; EBS3; EBS4; K14; K1C14; keratin 14; Keratin, type I cytoskeletal 14; Keratin-14; KRT14; NFJ;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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