Cytokeratin 17 (8C6) Mouse Monoclonal Antibody

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Catalog Number:MABN00866
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human Cytokeratin 17
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 48 kDa; Observed MW: 48 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human Cytokeratin 17

Target Background

Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.

Synonyms:Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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