Cytokeratin 8

Western Blot analysis of various cells using Cytokeratin 8 Polyclonal Antibody diluted at 1:2000

Western Blot analysis of various cells using Cytokeratin 8 Polyclonal Antibody diluted at 1:2000

Catalog Number:ABE2135
Conjugate:Unconjugated
Size:100ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Immunogen:The antiserum was produced against synthesized peptide derived from human Keratin 8. AA range:401-450
Reactivity:Hu,Ms,Rt
Applications:WB,IHC,IF,ELISA
Molecular Weight:53kD
Purification:Affinity Purified
Form:Liquid

keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Applications

WB,IHC,IF,ELISA

Immunogen

The antiserum was produced against synthesized peptide derived from human Keratin 8. AA range:401-450

Target Background

keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Western Blot analysis of various cells using Cytokeratin 8 Polyclonal Antibody diluted at 1:2000

Western Blot analysis of 293 cells using Cytokeratin 8 Polyclonal Antibody diluted at 1:2000

Immunofluorescence analysis of HeLa cells, using Keratin 8 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Keratin 8 Antibody. The picture on the right is blocked with the synthesized peptide.

No documents available.