Immunological Sciences

Cytokeratin 8 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN86307
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Cytokeratin 8
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:500,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:54 kDa; Observed MW:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:K8; KO; CK8; CK-8; CYK8; K2C8; CARD2

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:500,FC 1:20-1:50,IP 1:20-1:50

Immunogen

A synthetic peptide of human Cytokeratin 8

Target Background

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Synonyms:K8; KO; CK8; CK-8; CYK8; K2C8; CARD2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.