Immunological Sciences

DARPP-32 Rabbit Polyclonal Antibody

No images available

Catalog Number:ABN09793
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human DARPP-32. AA range:41-90
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein

Applications

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human DARPP-32. AA range:41-90

Target Background

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],function:Inhibitor of protein-phosphatase 1.,PTM:Dopamine- and cyclic AMP-regulated neuronal phosphoprotein.,PTM:Phosphorylation of Thr-34 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,

Synonyms:PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

No documents available.