Immunological Sciences

DCP1A (1Q16) Rabbit Monoclonal Antibody

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Catalog Number:MABN09845
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Dcp1a
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:63kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Dcp1a; HSA275986; Nbla00360; SMAD4IP1; SMIF;

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human Dcp1a

Target Background

Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:12417715). Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (PubMed:12417715). Contributes to the transactivation of target genes after stimulation by TGFB1 (PubMed:11836524). Essential for embryonic development (PubMed:33813271).

Synonyms:Dcp1a; HSA275986; Nbla00360; SMAD4IP1; SMIF;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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