Immunological Sciences

DDR2(Ascites) Mouse Monoclonal Antibody

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Catalog Number:MABN85933
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.
Reactivity:Human
Applications:WB 1:200-1:1600
Molecular Weight:96.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2, NTRKR3, TKT, TYRO10

Applications

WB 1:200-1:1600

Immunogen

This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.

Target Background

Receptor tyrosine kinases (RTKs) play a key role in thecommunication of cells with their microenvironment. These moleculesare involved in the regulation of cell growth, differentiation, andmetabolism. In several cases the biochemical mechanism by whichRTKs transduce signals across the membrane has been shown to beligand induced receptor oligomerization and subsequentintracellular phosphorylation. This autophosphorylation leads tophosphorylation of cytosolic targets as well as association withother molecules, which are involved in pleiotropic effects ofsignal transduction. RTKs have a tripartite structure withextracellular, transmembrane, and cytoplasmic regions. This geneencodes a member of a novel subclass of RTKs and contains adistinct extracellular region encompassing a factor VIII-likedomain. Alternative splicing in the 5' UTR results in multipletranscript variants encoding the same protein. [provided byRefSeq].

Synonyms:Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2, NTRKR3, TKT, TYRO10

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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