Immunological Sciences

DDX39B Rabbit Monoclonal Antibody

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Catalog Number:MABN86290
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human DDX39B
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:10-1:100
Molecular Weight:Calculated MW:49 kDa; Observed MW:49 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BAT1; UAP56; D6S81E

Applications

WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:10-1:100

Immunogen

Recombinant protein of human DDX39B

Target Background

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene. [provided by RefSeq, Feb 2011]

Synonyms:BAT1; UAP56; D6S81E

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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