Immunological Sciences

DiMethyl-Histone H3 (Lys4) Rabbit Monoclonal Antibody

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Catalog Number:MABN87486
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic methyl-peptide corresponding to residues surrounding Lys4 of human Histone H3
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:200-1:500
Molecular Weight:Calculated MW:15 kDa; Observed MW:17 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H3K4me; H3 histone; HIST1H3A; Histone cluster 1; H3a

Applications

WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:200-1:500

Immunogen

A synthetic methyl-peptide corresponding to residues surrounding Lys4 of human Histone H3

Target Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Synonyms:H3K4me; H3 histone; HIST1H3A; Histone cluster 1; H3a

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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