Dlx5 (19R2) Rabbit Monoclonal Antibody

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Catalog Number:MABN10029
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Dlx5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:500-1:1000
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Distal less homeo box 5; Dlx 5; Homeo box protein DLX 5;

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:500-1:1000

Immunogen

A synthetic peptide of human Dlx5

Target Background

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

Synonyms:Distal less homeo box 5; Dlx 5; Homeo box protein DLX 5;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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