DNA pol δ3 Rabbit Polyclonal Antibody

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Catalog Number:ABN10057
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human POLD3. AA range:411-460
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:51kDa
Purification:Affinity purification
Form:Liquid
Synonyms:POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human POLD3. AA range:411-460

Target Background

This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012],function:Required for optimal DNA polymerase delta activity.,subunit:Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA.,

Synonyms:POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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