Immunological Sciences

DNAM-1 Rabbit Polyclonal Antibody

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Catalog Number:ABN10073
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:38kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120

Target Background

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with PVR and PVRL2.,tissue specificity:Expressed by peripheral blood T-lymphocytes.,

Synonyms:CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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