DOCK2 Rabbit Monoclonal Antibody

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Catalog Number:MABN87691
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human DOCK2
Reactivity:Human
Applications:WB 1:1000-1:5000
Molecular Weight:Calculated MW:212 kDa; Observed MW:212 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IMD40

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human DOCK2

Target Background

The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]

Synonyms:IMD40

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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