DOCK2 Rabbit Monoclonal Antibody

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Catalog Number:MABN84588
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Dedicator of cytokinesis protein 2
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200
Molecular Weight:212 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DOCK 2; IMD40;;Dedicator of cytokinesis protein 2

Applications

WB 1:1000-1:2000,IHC 1:100-1:200

Immunogen

A synthesized peptide derived from human Dedicator of cytokinesis protein 2

Target Background

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Synonyms:DOCK 2; IMD40;;Dedicator of cytokinesis protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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