DOK1 Rabbit Monoclonal Antibody

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Catalog Number:MABN84610
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human DOK1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200
Molecular Weight:Calculated MW: 52 kDa ; Observed MW: 65 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DOK1; p62(dok); P62DOK; pp62;;DOK1

Applications

WB 1:1000-1:2000,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human DOK1

Target Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Synonyms:DOK1; p62(dok); P62DOK; pp62;;DOK1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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