Immunological Sciences

Doublecortin Rabbit Polyclonal Antibody

human brain tissue were subjected to SDS PAGE followed by western blot with DCX antibody at dilution of 1:600

human brain tissue were subjected to SDS PAGE followed by western blot with DCX antibody at dilution of 1:600

Catalog Number:AB-80651
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Immunogen:doublecortin
Reactivity:Hu, Ms, Rt
Applications:Western Blot: 1:500-1:2000 Immunohistochemistry: 1:20-1:200 Immunofluorescence: 1:20-1:200
Molecular Weight:40 kDa
Purification:≥95% as determined by SDS-PAGE
Form:Liquid
Synonyms:DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS

Applications

Western Blot: 1:500-1:2000 Immunohistochemistry: 1:20-1:200 Immunofluorescence: 1:20-1:200

Immunogen

doublecortin

Target Background

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

Synonyms:DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS

Storage

Store -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,

human brain tissue were subjected to SDS PAGE followed by western blot with DCX antibody at dilution of 1:600

Immunohistochemistry of paraffin-embedded human testis using DCX antibody at dilution of 1:100

Immunofluorescent analysis of SH-SY5Y cells using DCX antibody at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L)

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