DPD Rabbit Monoclonal Antibody

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Catalog Number:MABN86951
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human DPD
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:20-1:50
Molecular Weight:Calculated MW:111 kDa; Observed MW:111 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DHP; DPD; DHPDHASE

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:20-1:50

Immunogen

A synthetic peptide of human DPD

Target Background

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Synonyms:DHP; DPD; DHPDHASE

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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