Immunological Sciences

Dystrobrevin alpha Rabbit Monoclonal Antibody

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Catalog Number:MABN86914
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Dystrobrevin alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:Calculated MW:84 kDa; Observed MW:84 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DTN; DRP3; DTN-A; LVNC1; D18S892E

Applications

WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human Dystrobrevin alpha

Target Background

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Synonyms:DTN; DRP3; DTN-A; LVNC1; D18S892E

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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